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Research Articles

14. E3 Ring Finger Ubiquitin ligases: Structure and Drug Design

14. C.T. Chasapis, G.A. Spyroulias. E3 Ring Finger Ubiquitin ligases: Structure and Drug Design. Curr. Pharm. Design 31, 3716-3731 (2009).

13. Folding in Solution of the C – Catalytic Protein Fragment of Angiotensin Converting Enzyme

13. S.-S.M. Vamvakas, L. Leondiadis, G. Pairas, E. Manessi-Zoupa, G.A. Spyroulias, P. Cordopatis. Folding in Solution of the C – Catalytic Protein Fragment of Angiotensin Converting Enzyme. J. Pept. Sci. 15, 504-510 (2009). 10.1002/psc.1151

12. Insights into the anthrax lethal factor-substrate interaction and selectivity using docking and molecular dynamics simulations

12. G.A. Dalkas, A. Papakyriakou, A. Vlamis-Gardikas, G.A. Spyroulias. Insights into the anthrax lethal factor-substrate interaction and selectivity using docking and molecular dynamics simulations. Protein Science 18, 1774-1785 (2009). 10.1002/pro.169

11. NMR evidence of charge-dependent interaction between various PND V3 and CCR5 N-terminal peptides

11. P.A. Galanakis, N.G. Kandias, A. Rizos, D. Morikis, E. Krambovitis, G.A. Spyroulias. NMR evidence of charge-dependent interaction between various PND V3 and CCR5 N-terminal peptides. Biopolymers – Peptide Science 92, 94-109 (2009). 10.1002/bip.21127

10. High yield expression, and NMR characterization of Arkadia E3 Ubiquitin Ligase RING-H2 finger domain

10. N.G. Kandias, C.T. Chasapis, V. Episkopou, D. Bentrop, G.A. Spyroulias. High yield expression, and NMR characterization of Arkadia E3 Ubiquitin Ligase RING-H2 finger domain. BBRC 378, 498-502 (2009). 10.1016/j.bbrc.2008.11.055

9. Mechanism of CuA assembly

9. L. A. Abriata, L. Banci, I. Bertini, S. Ciofi-Baffoni, P. Gkazonis, G.A. Spyroulias, A.J. Vila, S. Wang. Mechanism of CuA assembly. Nature Chemical Biology 4, 599-601 (2008)10.1038/nchembio.110

8. Soluble guanylyl cyclase (sGC) activation by HMR-1766 (ataciguat) in cells exposed to oxidative stress

8. Z. Zhou, A. Pyriochou, A. Kotanidou, G.A. Dalkas, M. van Eickels, G.A. Spyroulias, C. Roussos A. Papapetropoulos. Soluble guanylyl cyclase (sGC) activation by HMR-1766 (ataciguat) in cells exposed to oxidative stress. American Journal of Physiology – Heart & Circulatory Physiology 295, Η1763-1771 (2008).10.1152/ajpheart.51.2008

7. Three isoforms of Complement Properdin Factor P in trout. Cloning, Expression, Gene Organization and Constrained Modeling. Dev. Comp. Immunol. 12, 1454-1466 (2008)

7. M. Chondrou, A.D. Papanastasiou, G.A. Spyroulias, I.K. Zarkadis. Three isoforms of Complement Properdin Factor P in trout. Cloning, Expression, Gene Organization and Constrained Modeling. Dev. Comp. Immunol. 12, 1454-1466 (2008). 10.1016/j.dci.2008.06.010

6. Low molecular weight inhibitors of the protease Anthrax Lethal Factor

6. G. Dalkas, A.Papakyriakou, A. Vlamis-Gardikas, G.A. Spyroulias. Low molecular weight inhibitors of the protease Anthrax Lethal Factor. Mini Reviews in Medicinal Chemistry 8, 290-306 (2008)10.2174/138955708783744083

5. Pyrrolo[2,3-a]carbazoles as potential CDK1 inhibitors. Synthesis, preliminary biological evaluation and binding mode through docking simulations

 5. M. A. Fousteris,A. Papakyriakou,A. Koutsourea, M. Manioudaki, E. Lampropoulou, E. Papadimitriou,G.A. Spyroulias, S.S. Nikolaropoulos. Pyrrolo[2,3-a]carbazoles as potential CDK1 inhibitors. Synthesis, preliminary biological evaluation and binding mode through docking simulations. J. Med. Chem 51, 1048-1052 (2008).