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Contact details

Georgios A. Spyroulias, PhD.
Department of Pharmacy
University of Patras
GR-26504 Patras, GREECE
Tel:    +30.2610.969950 (office)
+30.2610.969951 (terra silico)
+30.2610.969952 (terra vitro)
Fax:    +30.2610.969950
Email:  G.A.Spyroulias@upatras.gr

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N.G. Kandias, C.T. Chasapis, V. Episkopou, D. Bentrop, G.A. Spyroulias. High yield expression, and NMR characterization  of Arkadia E3 Ubiquitin Ligase RING-H2 finger domain.
BBRC 378, 498-502, (2009).
L.A. Abriata, L. Banci, I. Bertini, S. Ciofi-Baffoni, P. Gkazonis, G.A. Spyroulias, A.J. Vila, S. Wang. Mechanism of metal delivery to the CuA center interminal oxidases from bacteria: a redox menage-a-trois.
Nature Chemical Biology 4, 599-601, (2008).
Z. Zhou, A. Pyriochou, A. Kotanidou, G.A. Dalkas, M. van Eickels, G.A. Spyroulias, C. Roussos A. Papapetropoulos. Soluble guanylyl cyclase (sGC) activation by HMR-1766 (ataciguat) in cells exposed to oxidative stress.
American Journal of Physiology – Heart & Circulatory Physiology 295, Η1763-1771 (2008).
M. Chondrou, A.D. Papanastasiou, G.A. Spyroulias, I.K. Zarkadis. Three isoforms of Complement Properdin Factor P in trout. Cloning, Expression, Gene Organization and Constrained Modeling.
Developmental & Comparative Immunology 12, 1454-1466, (2008).
G. Dalkas, A.Papakyriakou, A. Vlamis-Gardikas, G.A.Spyroulias. Low molecular weight inhibitors of the protease Anthrax Lethal Factor.
Mini Reviews in Medicinal Chemistry 8, 290-306, (2008).
M.A. Fousteris, A. Papakyriakou, A. Koutsourea, M. Manioudaki, E. Lampropoulou, E. Papadimitriou, G.A. Spyroulias, S.S. Nikolaropoulos. Pyrrolo[2,3-a]carbazoles as potential CDK1 inhibitors. Synthesis, preliminary biological evaluation and binding mode through docking simulations.
Journal of Medicinal Chemistry 51, 1048-1052 (2008).
Z. Spyranti, G.A. Dalkas, G.A. Spyroulias, E.D. Matzourani, T. Mavromoustakos, I Friligou, T. Tselios, J. Matsoukas. Bioactive Conformations of Cyclic Myelin Basic Protein (MBP) Peptide Analogues: Exploring the Structural Requirements for Experimental Autoimmune Encephalomyelitis (EAE) Reversal.
Journal of Medicinal Chemistry 50, 6039-6047 (2007).
J. H. Agondanou, I. Nicolis, E. Curis, J. Purans, G.A. Spyroulias, A. G. Coutsolelos, S. Benazeth. Gadolinium Acetylacetonate Tetraphenyl Monoporphyrinate Complex and Some of its Derivatives: EXAFS Study and Molecular Dynamics Simulation.
Inorganic Chemistry 46, 6871-6879, (2007).
A. Papakyriakou, G.A. Spyroulias, E. Sturrock, E. Manessi-Zoupa, P. Cordopatis. Simulated Interactions between Angiotensin-Converting Enzyme and Substrate Gonadotropin-Releasing Hormone: Novel Insights into Domain-Selectivity.
Biochemistry 46, 8753-8765, (2007).
A.A. Zompra, V. Magafa, D.G. Chryssanthi, F.N. Lamari, G.A. Spyroulias, T. Maina, B. Nock, N.K. Karamanos, P. Cordopatis. Synthesis and Biological Evaluation of new GnRH Analogues on Pituitary and Breast Cancer cells.
Int. J. Pept. Res. & Theur. 13 (1-2), 143-149, (2007).
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