Contact details
Georgios A. Spyroulias, PhD.
Department of Pharmacy
University of Patras
Panepistimioupoli-Rion,
GR-26504 Patras, GREECE
Tel: +30.2610.969950 (office)
+30.2610.969951 (terra silico)
+30.2610.969952 (terra vitro)
Fax: +30.2610.969950
Email: G.A.Spyroulias@upatras.gr
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Now is: 2019-12-07 23:02
Selected publications Chasapis CT, Argyriou AI, Corringer PJ, Bentrop D, Spyroulias GA. Unravelling the Conformational Plasticity of the Extracellular Domain of a Prokaryotic nAChR Homologue in Solution by NMR. Biochemistry 50, 9681-9683 (2011) N. Dimitropoulos, A. Papakyriakou, G.A. Dalkas, C.T. Chasapis, K. Poulas, G.A. Spyroulias. A computational investigation on the role of glycosylation in the binding of alpha1 nicotinic acetylcholine receptor with two alpha-neurotoxins. Proteins: Structure, Function, Bioinformatics 79, 142-152 (2011) Dalkas GA, Chasapis CT, Gkazonis PV, Bentrop D, Spyroulias GA. Conformational dynamics of the anthrax lethal factor catalytic center. Current Pharmaceutical Design 31, 3716-3731 (2009). G.A. Dalkas, A. Papakyriakou , A. Vlamis-Gardikas , G.A. Spyroulias. Insights into the anthrax lethal factor-substrate interaction and selectivity using docking and molecular dynamics simulations. N.G. Kandias, C.T. Chasapis, V. Episkopou, D. Bentrop, G.A. Spyroulias. High yield expression, and NMR characterization of Arkadia E3 Ubiquitin Ligase RING-H2 finger domain. L.A. Abriata, L. Banci, I. Bertini, S. Ciofi-Baffoni, P. Gkazonis, G.A. Spyroulias, A.J. Vila, S. Wang. Mechanism of metal delivery to the CuA center interminal oxidases from bacteria: a redox menage-a-trois. M.A. Fousteris, A. Papakyriakou, A. Koutsourea, M. Manioudaki, E. Lampropoulou, E. Papadimitriou, G.A. Spyroulias, S.S. Nikolaropoulos. Pyrrolo[2,3-a]carbazoles as potential CDK1 inhibitors. Synthesis, preliminary biological evaluation and binding mode through docking simulations. Z. Spyranti, G.A. Dalkas, G.A. Spyroulias, E.D. Matzourani, T. Mavromoustakos, I Friligou, T. Tselios, J. Matsoukas. Bioactive Conformations of Cyclic Myelin Basic Protein (MBP) Peptide Analogues: Exploring the Structural Requirements for Experimental Autoimmune Encephalomyelitis (EAE) Reversal. A. Papakyriakou, G.A. Spyroulias, E. Sturrock, E. Manessi-Zoupa, P. Cordopatis. Simulated Interactions between Angiotensin-Converting Enzyme and Substrate Gonadotropin-Releasing Hormone: Novel Insights into Domain-Selectivity. L. Banci, I. Bertini, S. Ciofi-Baffoni, N.G. Kandias, G.A. Spyroulias, N.J. Robinson, M. Vanarotti, X.-C. Su. The delivery of copper for thylakoid import observed by NMR. |